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iEnhancer-DCLA: using the original sequence to identify enhancers and their strength based on a deep learning framework

Enhancers are small regions of DNA that bind to proteins, which enhance the transcription of genes. The enhancer may be located upstream or downstream of the gene. It is not necessarily close to the gene to be acted on, because the entanglement structure of chromatin allows the positions far apart i...

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Detalles Bibliográficos
Autores principales: Liao, Meng, Zhao, Jian-ping, Tian, Jing, Zheng, Chun-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664816/
https://www.ncbi.nlm.nih.gov/pubmed/36376800
http://dx.doi.org/10.1186/s12859-022-05033-x