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Applying machine learning to the pharmacokinetic modeling of cyclosporine in adult renal transplant recipients: a multi-method comparison

Objective: The aim of this study was to identify the important factors affecting cyclosporine (CsA) blood concentration and estimate CsA concentration using seven different machine learning (ML) algorithms. We also assessed the predictability of established ML models and previously built population...

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Detalles Bibliográficos
Autores principales: Mao, Junjun, Chen, Yuhao, Xu, Luyang, Chen, Weihuang, Chen, Biwen, Fang, Zhuo, Qin, Weiwei, Zhong, Mingkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664902/
https://www.ncbi.nlm.nih.gov/pubmed/36386138
http://dx.doi.org/10.3389/fphar.2022.1016399