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Small-molecule drugs development for Alzheimer's disease

Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative brain disorder with no effective therapeutic drugs currently. The complicated pathophysiology of AD is not well understood, although beta-amyloid (Aβ) cascade and hyperphosphorylated tau protein were regarded as the two...

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Detalles Bibliográficos
Autores principales: Yao, Weiwei, Yang, Huihui, Yang, Jinfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664938/
https://www.ncbi.nlm.nih.gov/pubmed/36389082
http://dx.doi.org/10.3389/fnagi.2022.1019412