Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice

Current vaccines against SARS-CoV-2 substantially reduce mortality, but protection against infection is less effective. Enhancing immunity in the respiratory tract, via mucosal vaccination, may provide protection against infection and minimise viral spread. Here, we report testing of a subunit vacci...

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Detalles Bibliográficos
Autores principales: Ashhurst, Anneliese S., Johansen, Matt D., Maxwell, Joshua W. C., Stockdale, Skye, Ashley, Caroline L., Aggarwal, Anupriya, Siddiquee, Rezwan, Miemczyk, Stefan, Nguyen, Duc H., Mackay, Joel P., Counoupas, Claudio, Byrne, Scott N., Turville, Stuart, Steain, Megan, Triccas, James A., Hansbro, Philip M., Payne, Richard J., Britton, Warwick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665025/
https://www.ncbi.nlm.nih.gov/pubmed/36379950
http://dx.doi.org/10.1038/s41467-022-34297-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665025/
https://www.ncbi.nlm.nih.gov/pubmed/36379950
http://dx.doi.org/10.1038/s41467-022-34297-3

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