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Hepatic Acat2 overexpression promotes systemic cholesterol metabolism and adipose lipid metabolism in mice

AIMS/HYPOTHESIS: Acetyl coenzyme A acetyltransferase (ACAT), also known as acetoacetyl-CoA thiolase, catalyses the formation of acetoacetyl-CoA from acetyl-CoA and forms part of the isoprenoid biosynthesis pathway. Thus, ACAT plays a central role in cholesterol metabolism in a variety of cells. Here...

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Detalles Bibliográficos
Autores principales: Ma, Zhimin, Huang, Zhengyun, Zhang, Chi, Liu, Xiangpeng, Zhang, Jie, Shu, Hui, Ma, Yue, Liu, Zhiwei, Feng, Yu, Chen, Xiyue, Kuang, Shihuan, Zhang, Yong, Jia, Zhihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665029/
https://www.ncbi.nlm.nih.gov/pubmed/36378328
http://dx.doi.org/10.1007/s00125-022-05829-9