Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers

Development of B-cell-based hepatitis C virus (HCV) vaccines that induce broadly neutralizing antibodies (bNAbs) is hindered by extensive sequence diversity and low immunogenicity of envelope glycoprotein vaccine candidates, most notably soluble E2 (sE2). To overcome this, we employed two-component...

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Detalles Bibliográficos
Autores principales: Prentoe, Jannick, Janitzek, Christoph M., Velázquez-Moctezuma, Rodrigo, Soerensen, Andreas, Jørgensen, Thomas, Clemmensen, Stine, Soroka, Vladislav, Thrane, Susan, Theander, Thor, Nielsen, Morten A., Salanti, Ali, Bukh, Jens, Sander, Adam F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665036/
https://www.ncbi.nlm.nih.gov/pubmed/36379958
http://dx.doi.org/10.1038/s41541-022-00570-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665036/
https://www.ncbi.nlm.nih.gov/pubmed/36379958
http://dx.doi.org/10.1038/s41541-022-00570-1

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