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Differential upregulation of AU-rich element-containing mRNAs in COVID-19

BACKGROUND: AU-rich elements (AREs) are located in the 3′UTRs of 22% of human mRNAs, including most transiently expressed inflammatory mediators. By default, AREs mark mRNAs for decay and translational inhibition, but this activity can be temporarily inhibited in case of infection to allow the onset...

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Detalles Bibliográficos
Autores principales: Bakheet, Tala, Khabar, Khalid S. A., Hitti, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665040/
https://www.ncbi.nlm.nih.gov/pubmed/36380320
http://dx.doi.org/10.1186/s40246-022-00433-9