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Catalpol relieved angiotensin II-induced blood–brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells

CONTEXT: Catalpol is a major bioactive constituent of Rehmannia glutinosa Libosch (Scrophulariaceae), a traditional Chinese medicine, which is widely used in multiple diseases, including hypertension. OBJECTIVES: To explore whether catalpol protects against angiotensin II (Ang II)-triggered blood–br...

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Detalles Bibliográficos
Autores principales: Xia, Yu, Lu, Yun Wei, Hao, Ren Juan, Yu, Gu Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665075/
https://www.ncbi.nlm.nih.gov/pubmed/36369944
http://dx.doi.org/10.1080/13880209.2022.2142801