Intra-articular injection PLGA blends sustained-release microspheres loaded with meloxicam: preparation, optimization, evaluation in vitro and in vivo

Meloxicam (MLX) is a commonly used drug in the clinical treatment of osteoarthritis, but it is associated with gastrointestinal adverse reactions. Therefore, in this study, we developed a sustained-release microsphere formulation of MLX for topical administration of knee joint. The MLX-loaded PLGA m...

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Detalles Bibliográficos
Autores principales: Sun, Zheng, Gu, Xuejing, Hao, Teng, Liu, Jiali, Gao, Rongrong, Li, Yanli, Yu, Bin, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665077/
https://www.ncbi.nlm.nih.gov/pubmed/36369759
http://dx.doi.org/10.1080/10717544.2022.2144545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665077/
https://www.ncbi.nlm.nih.gov/pubmed/36369759
http://dx.doi.org/10.1080/10717544.2022.2144545

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