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Intra-articular injection PLGA blends sustained-release microspheres loaded with meloxicam: preparation, optimization, evaluation in vitro and in vivo
Meloxicam (MLX) is a commonly used drug in the clinical treatment of osteoarthritis, but it is associated with gastrointestinal adverse reactions. Therefore, in this study, we developed a sustained-release microsphere formulation of MLX for topical administration of knee joint. The MLX-loaded PLGA m...
Autores principales: | Sun, Zheng, Gu, Xuejing, Hao, Teng, Liu, Jiali, Gao, Rongrong, Li, Yanli, Yu, Bin, Xu, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665077/ https://www.ncbi.nlm.nih.gov/pubmed/36369759 http://dx.doi.org/10.1080/10717544.2022.2144545 |
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