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Veratramine ameliorates pain symptoms in rats with diabetic peripheral neuropathy by inhibiting activation of the SIGMAR1-NMDAR pathway

CONTEXT: Veratramine may have a potential therapeutic effect for diabetic peripheral neuropathy (DPN). OBJECTIVE: To evaluate whether veratramine ameliorates neuropathic pain in a rat diabetic model. MATERIALS AND METHODS: Sprague–Dawley rats were used for a diabetic model induced by a streptozotoci...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Ye, Guangyao, Chen, Yuebo, Sheng, Chaoxu, Wang, Jianlin, Kong, Lingsi, Yuan, Liyong, Lin, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665081/
https://www.ncbi.nlm.nih.gov/pubmed/36373991
http://dx.doi.org/10.1080/13880209.2022.2136207