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The Heart’s Pacemaker Mimics Brain Cytoarchitecture and Function: Novel Interstitial Cells Expose Complexity of the SAN

BACKGROUND: The sinoatrial node (SAN) of the heart produces rhythmic action potentials, generated via calcium signaling within and among pacemaker cells. Our previous work has described the SAN as composed of a hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 (HCN4)-expressing...

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Detalles Bibliográficos
Autores principales: Bychkov, Rostislav, Juhaszova, Magdalena, Barrera, Miguel Calvo-Rubio, Donald, Lorenzo A.H., Coletta, Christopher, Shumaker, Chad, Moorman, Kayla, Sirenko, Syevda Tagirova, Maltsev, Alexander V., Sollott, Steven J., Lakatta, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665104/
https://www.ncbi.nlm.nih.gov/pubmed/36182566
http://dx.doi.org/10.1016/j.jacep.2022.07.003