Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation

Helminth endemic regions report lower COVID-19 morbidity and mortality. Here, we show that lung remodeling from a prior infection with a lung migrating helminth, Nippostrongylus brasiliensis, enhances viral clearance and survival of human-ACE2 transgenic mice challenged with SARS-CoV-2 (SCV2). This...

Descripción completa

Detalles Bibliográficos
Autores principales: Hilligan, Kerry L., Oyesola, Oyebola O., Namasivayam, Sivaranjani, Howard, Nina, Clancy, Chad S., Oland, Sandra D., Garza, Nicole L., Lafont, Bernard A. P., Johnson, Reed F., Mayer-Barber, Katrin D., Sher, Alan, Loke, P’ng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665339/
https://www.ncbi.nlm.nih.gov/pubmed/36380767
http://dx.doi.org/10.1101/2022.11.09.515832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665339/
https://www.ncbi.nlm.nih.gov/pubmed/36380767
http://dx.doi.org/10.1101/2022.11.09.515832

Ejemplares similares