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Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation

Helminth endemic regions report lower COVID-19 morbidity and mortality. Here, we show that lung remodeling from a prior infection with a lung migrating helminth, Nippostrongylus brasiliensis, enhances viral clearance and survival of human-ACE2 transgenic mice challenged with SARS-CoV-2 (SCV2). This...

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Detalles Bibliográficos
Autores principales:	Hilligan, Kerry L., Oyesola, Oyebola O., Namasivayam, Sivaranjani, Howard, Nina, Clancy, Chad S., Oland, Sandra D., Garza, Nicole L., Lafont, Bernard A. P., Johnson, Reed F., Mayer-Barber, Katrin D., Sher, Alan, Loke, P’ng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665339/ https://www.ncbi.nlm.nih.gov/pubmed/36380767 http://dx.doi.org/10.1101/2022.11.09.515832

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