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Impad1 and Syt11 work in an epistatic pathway that regulates EMT-mediated vesicular trafficking to drive lung cancer invasion and metastasis

Lung cancer is a highly aggressive and metastatic disease responsible for approximately 25% of all cancer-related deaths in the United States. Using high-throughput in vitro and in vivo screens, we have previously established Impad1 as a driver of lung cancer invasion and metastasis. Here we elucida...

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Detalles Bibliográficos
Autores principales: Bajaj, Rakhee, Rodriguez, B. Leticia, Russell, William K., Warner, Amanda N., Diao, Lixia, Wang, Jing, Raso, Maria G., Lu, Wei, Khan, Khaja, Solis, Luisa S., Batra, Harsh, Tang, Ximing, Fradette, Jared F., Kundu, Samrat T., Gibbons, Don L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665355/
https://www.ncbi.nlm.nih.gov/pubmed/36170810
http://dx.doi.org/10.1016/j.celrep.2022.111429