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The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease

Inflammatory cholestatic liver diseases, including Primary Sclerosing Cholangitis (PSC), are characterized by periportal inflammation with progression to cirrhosis. The objective of this study was to examine interactions between oxidative stress and autophagy in cholestasis. Using hepatic tissue fro...

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Detalles Bibliográficos
Autores principales: Shearn, Colin T., Anderson, Aimee L., Devereux, Michael W., Orlicky, David J., Michel, Cole, Petersen, Dennis R., Miller, Colin G., Harpavat, Sanjiv, Schmidt, Edward E., Sokol, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665405/
https://www.ncbi.nlm.nih.gov/pubmed/36378690
http://dx.doi.org/10.1371/journal.pone.0276879