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The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease
Inflammatory cholestatic liver diseases, including Primary Sclerosing Cholangitis (PSC), are characterized by periportal inflammation with progression to cirrhosis. The objective of this study was to examine interactions between oxidative stress and autophagy in cholestasis. Using hepatic tissue fro...
Autores principales: | Shearn, Colin T., Anderson, Aimee L., Devereux, Michael W., Orlicky, David J., Michel, Cole, Petersen, Dennis R., Miller, Colin G., Harpavat, Sanjiv, Schmidt, Edward E., Sokol, Ronald J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665405/ https://www.ncbi.nlm.nih.gov/pubmed/36378690 http://dx.doi.org/10.1371/journal.pone.0276879 |
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