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The case for FAT10 as a novel target in fatty liver diseases

Human leukocyte antigen F locus adjacent transcript 10 (FAT10) is a ubiquitin-like protein that targets proteins for degradation. TNFα and IFNγ upregulate FAT10, which increases susceptibility to inflammation-driven diseases like nonalcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatiti...

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Detalles Bibliográficos
Autores principales: Wimalarathne, Madushika M., Wilkerson-Vidal, Quiana C., Hunt, Emily C., Love-Rutledge, Sharifa T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665838/
https://www.ncbi.nlm.nih.gov/pubmed/36386217
http://dx.doi.org/10.3389/fphar.2022.972320