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A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint

The acquisition of movable jaws was a major event during vertebrate evolution. The role of NK3 homeobox 2 (Nkx3.2) transcription factor in patterning the primary jaw joint of gnathostomes (jawed vertebrates) is well known, however knowledge about its regulatory mechanism is lacking. In this study, w...

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Detalles Bibliográficos
Autores principales: Leyhr, Jake, Waldmann, Laura, Filipek-Górniok, Beata, Zhang, Hanqing, Allalou, Amin, Haitina, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665848/
https://www.ncbi.nlm.nih.gov/pubmed/36377467
http://dx.doi.org/10.7554/eLife.75749