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Top-Down Crawl: a method for the ultra-rapid and motif-free alignment of sequences with associated binding metrics
SUMMARY: Several high-throughput protein–DNA binding methods currently available produce highly reproducible measurements of binding affinity at the level of the k-mer. However, understanding where a k-mer is positioned along a binding site sequence depends on alignment. Here, we present Top-Down Cr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665867/ https://www.ncbi.nlm.nih.gov/pubmed/36179084 http://dx.doi.org/10.1093/bioinformatics/btac653 |