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Highly significant improvement of protein sequence alignments with AlphaFold2

MOTIVATION: Protein sequence alignments are essential to structural, evolutionary and functional analysis, but their accuracy is often limited by sequence similarity unless molecular structures are available. Protein structures predicted at experimental grade accuracy, as achieved by AlphaFold2, cou...

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Detalles Bibliográficos
Autores principales: Baltzis, Athanasios, Mansouri, Leila, Jin, Suzanne, Langer, Björn E, Erb, Ionas, Notredame, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665868/
https://www.ncbi.nlm.nih.gov/pubmed/36130276
http://dx.doi.org/10.1093/bioinformatics/btac625