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Integrating bulk and single-cell sequencing reveals the phenotype-associated cell subpopulations in sepsis-induced acute lung injury

The dysfunctional immune response and multiple organ injury in sepsis is a recurrent theme impacting prognosis and mortality, while the lung is the first organ invaded by sepsis. To systematically elucidate the transcriptomic changes in the main constituent cells of sepsis-injured lung tissue, we ap...

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Detalles Bibliográficos
Autores principales: Wang, Fuquan, Chen, Ming, Ma, Jiamin, Wang, Chenchen, Wang, Jingxu, Xia, Haifa, Zhang, Dingyu, Yao, Shanglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666384/
https://www.ncbi.nlm.nih.gov/pubmed/36405762
http://dx.doi.org/10.3389/fimmu.2022.981784