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Microfluidic dose–response platform to track the dynamics of drug response in single mycobacterial cells
Preclinical analysis of drug efficacy is critical for drug development. However, conventional bulk-cell assays statically assess the mean population behavior, lacking resolution on drug-escaping cells. Inaccurate estimation of efficacy can lead to overestimation of compounds, whose efficacy will not...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666435/ https://www.ncbi.nlm.nih.gov/pubmed/36379978 http://dx.doi.org/10.1038/s41598-022-24175-9 |