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Crystal structure of semi-synthetic obelin-v after calcium induced bioluminescence implies coelenteramine as the main reaction product

Coelenterazine-v (CTZ-v), a synthetic vinylene-bridged π-extended derivative, is able to significantly alter bioluminescence spectra of different CTZ-dependent luciferases and photoproteins by shifting them towards longer wavelengths. However, Ca(2+)-regulated photoproteins activated with CTZ-v disp...

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Detalles Bibliográficos
Autores principales: Natashin, Pavel V., Eremeeva, Elena V., Shevtsov, Mikhail B., Kovaleva, Margarita I., Bukhdruker, Sergey S., Dmitrieva, Daria A., Gulnov, Dmitry V., Nemtseva, Elena V., Gordeliy, Valentin I., Mishin, Alexey V., Borshchevskiy, Valentin I., Vysotski, Eugene S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666459/
https://www.ncbi.nlm.nih.gov/pubmed/36379962
http://dx.doi.org/10.1038/s41598-022-24117-5