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Influence of tramadol on bacterial burden in the standard neutropenic thigh infection model

The neutropenic thigh infection model is one of the standard models in pharmacokinetic/ pharmacodynamic (PK/PD) characterization of novel antibacterials which are urgently needed due to the rise of antimicrobial resistance. The model enables to investigate PK/PD parameters crucial for translation of...

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Detalles Bibliográficos
Autor principal: Rox, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666522/
https://www.ncbi.nlm.nih.gov/pubmed/36380116
http://dx.doi.org/10.1038/s41598-022-24111-x