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Influence of tramadol on bacterial burden in the standard neutropenic thigh infection model
The neutropenic thigh infection model is one of the standard models in pharmacokinetic/ pharmacodynamic (PK/PD) characterization of novel antibacterials which are urgently needed due to the rise of antimicrobial resistance. The model enables to investigate PK/PD parameters crucial for translation of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666522/ https://www.ncbi.nlm.nih.gov/pubmed/36380116 http://dx.doi.org/10.1038/s41598-022-24111-x |