Cargando…
Influence of tramadol on bacterial burden in the standard neutropenic thigh infection model
The neutropenic thigh infection model is one of the standard models in pharmacokinetic/ pharmacodynamic (PK/PD) characterization of novel antibacterials which are urgently needed due to the rise of antimicrobial resistance. The model enables to investigate PK/PD parameters crucial for translation of...
Autor principal: | Rox, K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666522/ https://www.ncbi.nlm.nih.gov/pubmed/36380116 http://dx.doi.org/10.1038/s41598-022-24111-x |
Ejemplares similares
-
Neutropenic Rat Thigh Infection Model for Evaluation of the Pharmacokinetics/Pharmacodynamics of Anti-Infectives
por: Yedle, Randhir, et al.
Publicado: (2023) -
Determination of Therapeutic Equivalence of Generic Products of Gentamicin in the Neutropenic Mouse Thigh Infection Model
por: Zuluaga, Andres F., et al.
Publicado: (2010) -
Pharmacodynamics of nine generic products of amikacin compared with the innovator in the neutropenic mouse thigh infection model
por: Zuluaga, Andres F., et al.
Publicado: (2015) -
Synergistic Effect of a Pleuromutilin Derivative with Tetracycline against Streptococcus suis In Vitro and in the Neutropenic Thigh Infection Model
por: Chen, Fang, et al.
Publicado: (2020) -
In vivo pharmacodynamics of lefamulin, the first systemic pleuromutilin for human use, in a neutropenic murine thigh infection model
por: Wicha, Wolfgang W, et al.
Publicado: (2019)