Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma

Ocular hypertension is a significant risk factor for vision loss in glaucoma due to the death of retinal ganglion cells (RGCs). This study investigated the effects of the antiapoptotic peptides peptain-1 and peptain-3a on RGC death in vitro in rat primary RGCs and in mouse models of ocular hypertens...

Descripción completa

Detalles Bibliográficos
Autores principales: Nam, Mi-Hyun, Stankowska, Dorota L., Johnson, Gretchen A., Nahomi, Rooban B., Pantcheva, Mina B., Nagaraj, Ram H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666629/
https://www.ncbi.nlm.nih.gov/pubmed/36379926
http://dx.doi.org/10.1038/s41419-022-05407-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666629/
https://www.ncbi.nlm.nih.gov/pubmed/36379926
http://dx.doi.org/10.1038/s41419-022-05407-2

Ejemplares similares