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Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma

Ocular hypertension is a significant risk factor for vision loss in glaucoma due to the death of retinal ganglion cells (RGCs). This study investigated the effects of the antiapoptotic peptides peptain-1 and peptain-3a on RGC death in vitro in rat primary RGCs and in mouse models of ocular hypertens...

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Detalles Bibliográficos
Autores principales:	Nam, Mi-Hyun, Stankowska, Dorota L., Johnson, Gretchen A., Nahomi, Rooban B., Pantcheva, Mina B., Nagaraj, Ram H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666629/ https://www.ncbi.nlm.nih.gov/pubmed/36379926 http://dx.doi.org/10.1038/s41419-022-05407-2

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