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Reciprocal best structure hits: using AlphaFold models to discover distant homologues
MOTIVATION: The conventional methods to detect homologous protein pairs use the comparison of protein sequences. But the sequences of two homologous proteins may diverge significantly and consequently may be undetectable by standard approaches. The release of the AlphaFold 2.0 software enables the p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666668/ https://www.ncbi.nlm.nih.gov/pubmed/36408459 http://dx.doi.org/10.1093/bioadv/vbac072 |