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Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps

Forsythiaside B (FTB) is one of the main components of Forsythia suspensa (Thunb.) Vahl and exerts anti-inflammatory and anti-oxidative effects. However, its mechanism of action as a treatment for sepsis remains unclear. In this study, we developed a rat model of sepsis using cecal ligation and punc...

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Detalles Bibliográficos
Autores principales: He, Wenju, Xi, Qiang, Cui, Huantian, Zhang, Pingping, Huang, Rui, Wang, Taihuan, Wang, Dongqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666896/
https://www.ncbi.nlm.nih.gov/pubmed/36408247
http://dx.doi.org/10.3389/fphar.2022.1022985