Cargando…

Aza-BODIPY based carbonic anhydrase IX: Strategy to overcome hypoxia limitation in photodynamic therapy

Hypoxia caused by photodynamic therapy (PDT) is a major hurdle to cancer treatment since it can promote recurrence and progression by activating angiogenic factors, lowering therapeutic efficacy dramatically. In this work, AZB-I-CAIX(2) was developed as a carbonic anhydrase IX (CAIX)-targeting NIR p...

Descripción completa

Detalles Bibliográficos
Autores principales: Pewklang, Thitima, Chansaenpak, Kantapat, Bakar, Siti Nursyahirah, Lai, Rung-Yi, Kue, Chin Siang, Kamkaew, Anyanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666899/
https://www.ncbi.nlm.nih.gov/pubmed/36405312
http://dx.doi.org/10.3389/fchem.2022.1015883