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Cis- and trans-regulation by histone H4 basic patch R17/R19 in metazoan development

The histone H4 basic patch is critical for chromatin structure and regulation of the chromatin machinery. However, the biological roles of these positively charged residues and the mechanisms by which they regulate gene expression remain unclear. In this study, we used histone mutagenesis to investi...

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Detalles Bibliográficos
Autores principales: Zhang, Xuedi, Wu, Xiangyu, Peng, Ju, Sun, Angyang, Guo, Yan, Fu, Pengchong, Gao, Guanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667139/
https://www.ncbi.nlm.nih.gov/pubmed/36382370
http://dx.doi.org/10.1098/rsob.220066