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Cis- and trans-regulation by histone H4 basic patch R17/R19 in metazoan development
The histone H4 basic patch is critical for chromatin structure and regulation of the chromatin machinery. However, the biological roles of these positively charged residues and the mechanisms by which they regulate gene expression remain unclear. In this study, we used histone mutagenesis to investi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667139/ https://www.ncbi.nlm.nih.gov/pubmed/36382370 http://dx.doi.org/10.1098/rsob.220066 |