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Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity

G6PD (glucose-6-phosphate dehydrogenase) is the rate-limiting enzyme in the oxidative pentose phosphate pathway that can generate cytosolic NADPH for biosynthesis and oxidative defense. Since cytosolic NADPH can be compensatively produced by other sources, the enzymatic activity deficiency alleles o...

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Detalles Bibliográficos
Autores principales: Jin, Xiaohan, Li, Xuexue, Li, Lifang, Zhong, Benfu, Hong, Yang, Niu, Jing, Li, Binghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667318/
https://www.ncbi.nlm.nih.gov/pubmed/36243112
http://dx.doi.org/10.1016/j.jbc.2022.102587