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Facile, rapid and efficient isolation of circulating tumor cells using aptamer-targeted magnetic nanoparticles integrated with a microfluidic device

Facile and sensitive detection and isolation of circulating tumor cells (CTCs) was achieved using the aptamer-targeted magnetic nanoparticles (Apt-MNPs) in conjugation with a microfluidic device. Apt-MNPs were developed by the covalent attachment of anti-MUC1 aptamer to the silica-coated magnetic na...

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Detalles Bibliográficos
Autores principales: Kajani, Abolghasem Abbasi, Rafiee, Laleh, Samandari, Mohamadmahdi, Mehrgardi, Masoud Ayatollahi, Zarrin, Bahare, Javanmard, Shaghayegh Haghjooy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667373/
https://www.ncbi.nlm.nih.gov/pubmed/36425208
http://dx.doi.org/10.1039/d2ra05930d