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CRISPR/Cas9‐mediated deletion of Fam83h induces defective tooth mineralization and hair development in rabbits

Family with sequence similarity 83 members H (Fam83h) is essential for dental enamel formation. Fam83h mutations cause human amelogenesis imperfecta (AI), an inherited disorder characterized by severe hardness defects in dental enamel. Nevertheless, previous studies showed no enamel defects in Fam83...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxin, Yang, Jie, Yao, Haobin, Zhang, Zhongtian, Song, Yuning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667525/
https://www.ncbi.nlm.nih.gov/pubmed/36300761
http://dx.doi.org/10.1111/jcmm.17597