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CRISPR/Cas9‐mediated deletion of Fam83h induces defective tooth mineralization and hair development in rabbits
Family with sequence similarity 83 members H (Fam83h) is essential for dental enamel formation. Fam83h mutations cause human amelogenesis imperfecta (AI), an inherited disorder characterized by severe hardness defects in dental enamel. Nevertheless, previous studies showed no enamel defects in Fam83...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667525/ https://www.ncbi.nlm.nih.gov/pubmed/36300761 http://dx.doi.org/10.1111/jcmm.17597 |