ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells

BACKGROUND: Intratumoral heterogeneity is the primary challenge in the treatment of glioblastoma (GBM). The presence of glioma stem cells (GSCs) and their conversion between different molecular phenotypes contribute to the complexity of heterogeneity, culminating in preferential resistance to radiot...

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Detalles Bibliográficos
Autores principales: Gao, Zijie, Xu, Jianye, Fan, Yang, Zhang, Zongpu, Wang, Huizhi, Qian, Mingyu, Zhang, Ping, Deng, Lin, Shen, Jie, Xue, Hao, Zhao, Rongrong, Zhou, Teng, Guo, Xing, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667586/
https://www.ncbi.nlm.nih.gov/pubmed/36380368
http://dx.doi.org/10.1186/s13046-022-02526-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667586/
https://www.ncbi.nlm.nih.gov/pubmed/36380368
http://dx.doi.org/10.1186/s13046-022-02526-8

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