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Synthesis and bioactivities evaluation of quinazolin-4(3H)-one derivatives as α-glucosidase inhibitors

The development of new antidiabetes agents is necessary to obtain optimal glycemic control and overcome its complications. Different quinazolin-4(3H)-one bearing phenoxy-acetamide derivatives (7a–r) were designed and synthesized to develop α-glucosidase inhibitors. All the synthesized derivatives we...

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Detalles Bibliográficos
Autores principales: Moheb, Mahshid, Iraji, Aida, Dastyafteh, Navid, Khalili Ghomi, Minoo, Noori, Milad, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Rasekh, Fatemeh, Larijani, Bagher, Zomorodian, Kamiar, Sadat-Ebrahimi, Seyed Esmaeil, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667588/
https://www.ncbi.nlm.nih.gov/pubmed/36380337
http://dx.doi.org/10.1186/s13065-022-00885-z