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Sphingosine kinase 1 contributes to the metastatic potential of epithelial ovarian cancer to the adipocyte-rich niche

Unlike many solid tumors, epithelial ovarian cancer (EOC) has a clear metastatic predilection to the adipocyte-rich niche, especially the omentum. However, the underlying mechanism driving this process remains incomplete. Here we show that SphK1 is over-expressed in omental metastases compared with...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Ye, Taiyang, Wang, Wenjing, Song, Keqi, Zhu, Jie, Dai, Lan, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667684/
https://www.ncbi.nlm.nih.gov/pubmed/36384540
http://dx.doi.org/10.1186/s40164-022-00358-y