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PEO-b-PBD Diblock Copolymers Induce Packing Defects in Lipid/Hybrid Membranes and Improve Insertion Rates of Natively Folded Peptides

[Image: see text] Hybrid membranes assembled from biological lipids and synthetic polymers are a promising scaffold for the reconstitution and utilization of membrane proteins. Recent observations indicate that inclusion of small fractions of polymer in lipid membranes can improve protein folding an...

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Detalles Bibliográficos
Autores principales: Steinkühler, Jan, Jacobs, Miranda L., Boyd, Margrethe A., Villaseñor, Citlayi G., Loverde, Sharon M., Kamat, Neha P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667879/
https://www.ncbi.nlm.nih.gov/pubmed/36318160
http://dx.doi.org/10.1021/acs.biomac.2c00936