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Coordinating transcription and replication to mitigate their conflicts in early Drosophila embryos
Collisions between transcribing RNA polymerases and DNA replication forks are disruptive. The threat of collisions is particularly acute during the rapid early embryonic cell cycles of Drosophila when S phase occupies the entirety of interphase. We hypothesize that collision-avoidance mechanisms saf...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667882/ https://www.ncbi.nlm.nih.gov/pubmed/36261005 http://dx.doi.org/10.1016/j.celrep.2022.111507 |