Cargando…

Coordinating transcription and replication to mitigate their conflicts in early Drosophila embryos

Collisions between transcribing RNA polymerases and DNA replication forks are disruptive. The threat of collisions is particularly acute during the rapid early embryonic cell cycles of Drosophila when S phase occupies the entirety of interphase. We hypothesize that collision-avoidance mechanisms saf...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Chun-Yi, Kemp, James P., Duronio, Robert J., O’Farrell, Patrick H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667882/
https://www.ncbi.nlm.nih.gov/pubmed/36261005
http://dx.doi.org/10.1016/j.celrep.2022.111507