Aryl diazonium intermediates enable mild DNA-compatible C–C bond formation for medicinally relevant combinatorial library synthesis

Forging carbon–carbon (C–C) linkage in DNA-encoded combinatorial library synthesis represents a fundamental task for drug discovery, especially with broad substrate scope and exquisite functional group tolerance. Here we reported the palladium-catalyzed Suzuki–Miyaura, Heck and Hiyama type cross-cou...

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Detalles Bibliográficos
Autores principales: Li, Xianfeng, Zhang, Juan, Liu, Changyang, Sun, Jie, Li, Yangfeng, Zhang, Gong, Li, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667928/
https://www.ncbi.nlm.nih.gov/pubmed/36425486
http://dx.doi.org/10.1039/d2sc04482j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667928/
https://www.ncbi.nlm.nih.gov/pubmed/36425486
http://dx.doi.org/10.1039/d2sc04482j

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