Isobactins: O-acyl isopeptide prodrugs of teixobactin and teixobactin derivatives

The antibiotic teixobactin is a promising drug candidate against drug-resistant pathogens, such as MRSA and VRE, but forms insoluble gels that may limit intravenous administration. O-Acyl isopeptide prodrug analogues of teixobactin circumvent the problem of gel formation while retaining antibiotic a...

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Detalles Bibliográficos
Autores principales: Jones, Chelsea R., Guaglianone, Gretchen, Lai, Grant H., Nowick, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667932/
https://www.ncbi.nlm.nih.gov/pubmed/36425497
http://dx.doi.org/10.1039/d2sc02670h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667932/
https://www.ncbi.nlm.nih.gov/pubmed/36425497
http://dx.doi.org/10.1039/d2sc02670h

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