Cargando…

A focus on the discovery of potent and selective cyclic peptide scaffolds for drug development

In the past, cyclic peptide drugs were commonly discovered by isolation of natural products. However, recent efforts predominantly use high-throughput synthetic or genetically encoded libraries to find potent and selective hits against a range of challenging therapeutic targets. Kawamura et al. (Che...

Descripción completa

Detalles Bibliográficos
Autores principales: Saunders, George J., Yudin, Andrei K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667955/
https://www.ncbi.nlm.nih.gov/pubmed/36425493
http://dx.doi.org/10.1039/d2sc90214a