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A focus on the discovery of potent and selective cyclic peptide scaffolds for drug development
In the past, cyclic peptide drugs were commonly discovered by isolation of natural products. However, recent efforts predominantly use high-throughput synthetic or genetically encoded libraries to find potent and selective hits against a range of challenging therapeutic targets. Kawamura et al. (Che...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667955/ https://www.ncbi.nlm.nih.gov/pubmed/36425493 http://dx.doi.org/10.1039/d2sc90214a |