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The potential of mRNA expression evaluation in predicting HER2 positivity in gastroesophageal cancer

Gastroesophageal cancer (GEC) is an aggressive disease characterized by a high frequency of metastasis and poor overall survival rates. GEC presents HER2 overexpression in 5 to 25% of tumors eligible for HER2-targeted therapy. HER2 evaluation requires protein levels and copy number alteration analys...

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Detalles Bibliográficos
Autores principales: de Oliveira, I.M., Nicolau-Neto, P., Fernandes, P.V., Lavigne, T.S., Neves, P.F., Tobar, J.C., Soares-Lima, S.C., Simão, T.A., Pinto, L.F. Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668082/
https://www.ncbi.nlm.nih.gov/pubmed/36383805
http://dx.doi.org/10.1590/1414-431X2022e12428