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HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy

The lung is an understudied site of HIV persistence. We isolated 898 subgenomic proviral sequences (nef) by single-genome approaches from blood and lung from nine individuals on long-term suppressive antiretroviral therapy (ART), and characterized genetic diversity and compartmentalization using for...

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Detalles Bibliográficos
Autores principales: Shahid, Aniqa, Jones, Bradley R., Yang, Julia S. W., Dong, Winnie, Shaipanich, Tawimas, Donohoe, Kathryn, Brumme, Chanson J., Joy, Jeffrey B., Leung, Janice M., Brumme, Zabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668181/
https://www.ncbi.nlm.nih.gov/pubmed/36331974
http://dx.doi.org/10.1371/journal.ppat.1010613