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HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy
The lung is an understudied site of HIV persistence. We isolated 898 subgenomic proviral sequences (nef) by single-genome approaches from blood and lung from nine individuals on long-term suppressive antiretroviral therapy (ART), and characterized genetic diversity and compartmentalization using for...
Autores principales: | Shahid, Aniqa, Jones, Bradley R., Yang, Julia S. W., Dong, Winnie, Shaipanich, Tawimas, Donohoe, Kathryn, Brumme, Chanson J., Joy, Jeffrey B., Leung, Janice M., Brumme, Zabrina L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668181/ https://www.ncbi.nlm.nih.gov/pubmed/36331974 http://dx.doi.org/10.1371/journal.ppat.1010613 |
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