Genome-wide quantification of contributions to sexual fitness identifies genes required for spore viability and health in fission yeast

Numerous genes required for sexual reproduction remain to be identified even in simple model species like Schizosaccharomyces pombe. To address this, we developed an assay in S. pombe that couples transposon mutagenesis with high-throughput sequencing (TN-seq) to quantitatively measure the fitness c...

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Detalles Bibliográficos
Autores principales: Billmyre, R. Blake, Eickbush, Michael T., Craig, Caroline J., Lange, Jeffrey J., Wood, Christopher, Helston, Rachel M., Zanders, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668190/
https://www.ncbi.nlm.nih.gov/pubmed/36301993
http://dx.doi.org/10.1371/journal.pgen.1010462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668190/
https://www.ncbi.nlm.nih.gov/pubmed/36301993
http://dx.doi.org/10.1371/journal.pgen.1010462

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